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THE MEASUREMENT AND ANALYSIS OF FOOD ALLERGEN-SPECIFIC IGE IN INFANTILE ASTHMA

ZHAO J, TAN LW, CAO L, FU J, CHEN YZ

Capital Institute of Pediatrics, Beijing, China

Object: To realize the proportion of food allergy in infantile asthma

Method: 158 tests of food specific serum IgE (sIgE) were performed on patients of infantile asthma.

Result: 43% of the patients have been found to have food-specific sIgE. Among all the cases we tested, the percentage of high level of (>grade 3, 3.5ku/L) sIgE specific to various food as egg white, milk, peanut, wheat and soy bean were 8%, 8%, 5%; 4%, and 1.3% respectively. The positive sIgE values to beef and mutton were low. In the clinic, only two patients in the group could provide the definite case history of inducing asthma after taking food; most other patients had complications as eczema, allergic urticaria or rhinitis. At the same time, Pharmacia CAP Phadiatop inhalation test was measured in 130 patients of same group of infantile asthma. 44 (34%) patients were allergic to the inhaled allergen, 45% (58) of the patients were allergized to the food allergen (P<0.05).

Conclusion: It suggests that food sIgE has the preponderance over inhalation sIgE in infantile asthma patients' serum.