0042

IGA-IC ASSAYED IN CHILDREN WITH IGA NEPHROPATHY AND HENOCH-SCHONNLEIN PURROURA NEPHRITIS

Shen y , Zhang Y-W , Zhang G-J , Wang D-M, Meng Q, Chen B-Y

Beijing Children’s Hospital Affiliated to Capital University of Medical Sciences, Beijing, China

Objective: Research on the clinical significance of IgA-IC assay to IgA Nephropathy (IgAN) and Henoch-Schonnlein Purroura Nephritis (HSPN) in children.

Methods: Congluuttinin-ELISA was applied to assay 198 patients divided into 4 groups corresponding to IgAN, HSPN, urinary tract infection and glomerulonephritis and 30 healthy children as one control group.

Results: No significant difference of IgA-IC was found between any two of above groups. Conclusions: There is no diagnostic value of IgA-IC assay to IgAN and HSPN. IgA-IC change has no relation with IgAN pathology.