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RESEARCH OF INFECTION OF HUMAN HERPES VIRUS TYPE-8 IN THE MOTHERS AND
THEIR INFANTS OF Urumqi and Altai regions Sun H1 ,
Chen G-M2, Wang L-T3, Jia N1, Du W-H1,
Zeng Y2 1 Institute of Pediatrics
of Xinjiang, Urumqi, China 2 Institute of Virology of
Chinese Academy of Preventive Medicine 3 Altai Region’s Hospital Objective: The aim of this study
was to know the status of infection of human herpes virus type-8 (HHV-8) in
the mothers and their infants of Urumqi and Altai regions. Methods: We use BCBL-1 cell line
as antigen and collected 406 match sera samples of different nationalities
(Uighur, Kazak and Han nationality) of mothers and their infants (cord
blood) from Urumqi and Altai regions of xinjiang A.R, tested for
determination of HHV-8 IgG and IgM antibody by immunofluorescence assay. Results: Results show that HHV-8
IgG antibody positive rate of mothers and their infants of Uighur
nationality was 22.9%(24/105), Han nationality was 5.4%(8/149) in Urumqi
region and Kazak nationality was 26.1%(27/103), Han nationality was
8.1%(4/49) in Altai region. The IgM positive rate of mothers was
0.7%(3/406) and their infants was 0.5%(2/406). Conclusions: This date illustrate
that the infective rate of HHV-8 of mothers and their infants in different
nationality was different. Uighur was higher than Han in Urumqi region and
Kazak was higher than Han in Altai region too (p<0.05). The infants of
HHV-8 IgG and IgM antibody positive need to follow-up.