0083
Liu YF, Zeng Li. Department of
Pediatrics, First Affiliated Hospital of Henan Medical University, Zhengzhou.
China. Objective: To study on the changes
of red cell immunity in children with acute infectious diseases including
acute upper respiratory infections (AURI), acute bronchopneumonia and acute
infectious diarrhea and control group (40 cases normal children. Methods: The indexes of red cell
immune function including: the rosette formation of RBC-C3b receptor (RBC-C3bRR),
the rosette formation RBC immunocomplex (RBC-ICR), the rosette formation of
the RBC enhancing factors (REF) and the rosette formation RBC inhibitory
factors (RIF), which were detected by Ys yeast methods. Results: the RBC-C3bRR, RBC-ICR, REF and RIF in control group were as
following respectively: RBC-C3bRR 13.140±1.606, RBC-ICR 6.785±1.452, REF
64.637±13.804 and RIF 20.283±8.251; 54 cases children with AURI were:
11.237±3.744, 4.909±2.879, 44.909±12.405 and 22.920±4.928; 74 cases
children with acute bronchopneumonia were: 8.016±2.725, 5.531±1.397, 51.809±13.689
and 22.203±5.733; 66 cases children with acute infectious diarrhea were: 8.641±2.137, 6.706±1.800, 48.700±13.410
and 24.944±6.155; the RBC-C3bRR, RBC-ICR, REF in children with AURI
and acute bronchopneumonia were
lower than that of control group
(p<0.05), and EIF was the same as normal(p>0.05); the RBC-C3bRR, REF
and RIF in children with acute
infectious diarrhea were lower than
that of control group (p<0.05), and the RBC-ICR was higher than that of control
group (p<0.05). Conclusion: The results show that the red cell immune function in children with acute
infectious diseases is decreased and the changes of red cell immunity in children with acute infectious diseases are probably relation to the kinds of
pathogenic organisms and infectious parts. Key words: RBC-C3b receptor (RBC-C3bR);
RBC immunocomplex; the rosette formation of the RBC enhancing factors (REF);
the rosette formation of the RBC inhibitory factors (RIF); acute upper
respiratory infections (AURI); acute bronchopneumonia; acute infectious
diarrhea
STUDY ON THE RED CELL
IMMUNE FUNCTION IN CHILDREN WITH ACUTE INFECTIOUS DISEASES