0105

EPIDEMIOLOGICAL STUDY ON PEDIATRIC ACUTE LUNG INJURY

Zhu LQ, Chen X

Jiangxi Children’s Hospital, Nanchang, China

Objective: To study the epidemiology of pediatric acute lung injury (ALI) and its advanced stage - acute respiratory distress syndrome (ARDS). Methods: To study the patients admitted to Jiangxi Children’s Hospital of China and pediatric intensive care unit (PICU) of this hospital during February 1996 through January 2001 according to the international and national diagnostic criteria of ALI, ARDS, systemic inflammatory response syndrome (SIRS) and high risk scoring system. To identify and analyze the risk factors which affect the mortality of ALI/ARDS using univariate analysis and u test as statistical methods.

Results: 64 ALI/ARDS patients enrolled in total of 76114 hospital admissions and 1698 PICU critically ill admissions during this period of time, the morbidity were 0.084% and 3.77% respectively. The morbidity of 3 major diseases which caused ALI/ARDS were 0.65% in sepsis, 0.12% in pneumonia and 0.54% in accidents respectively. The mortality of this study was 34.38%, the relative risk {RR} of 7 risk factors or diseases which affected mortality were in order of SIRS, extrapulmonary organ involvements, less pao2/fi02, sepsis, pediatric high risk score, pneumonia and accidents.

Conclusions: The morbidity of ALI/ARDS is increasing yearly which may be because it is more likely to be recognized by physicians with more awareness of this disease. The mortality remains high, the risk factors associated with mortality are SIRS, extrapulmonary organ involvements, pediatric high risk score and less pao2/fio2, whereas sepsis is major disease causing ALI/ARDS and death then followed by accidents and pneumonia.