ASSOCIATION BETWEEN WHITE MICROTHROMBUS, PLASMA D-DIMER LEVELS AND NEPHROTIC SYNDROME COMPLICATED WITH RENAL VEIN THROMBOSIS IN CHILDREN

Yang D S, Han ZM, Chen XD, Xing Y

The First Affiliated Hospital, Xinxiang Medical College, Henan Weihui, China

 

Objective: To study the association between white microthrombus, plasma D-dimer levels and renal vein thrombosis (RVT) in nephroic syndrome (NS) patients.

Methods: 50 normal children were chosen as normal control group. 100 NS cases were chosen. RVT can be diagnosed by continuous thin-layer reinforced helico-CT for renal vein (thickness of CT-layer is 2 mm). 100 patients were divided into two groups. The group(n=88) was NS patients without RVT and the group(n=12) was NS patients with RVT. White microthrombus were examined by WS-9 surface microcirculation detector. Plasma D-Dimer levers were detected by ELISA.

Results: The positive rates of white microthrombus in the groupwas much higher than that in the group (91.6%, 18.3%, p0.005. The plasma D-dimer levels were significantly higher in the group (2.06±0.57)mg/L than that of the group (0.33±0.09)mg/L and the normal control group(0.28±0.06)mg/L(p0.01, p0.001, and that of  the group had no difference compared with that of the normal control group(p0.05).

Conclusion: In NS patients, positive white microthrombus and plasma D-dimer levels increasing correlate closely with RVT.

 

 
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