ASSOCIATION
BETWEEN WHITE MICROTHROMBUS, PLASMA D-DIMER LEVELS AND NEPHROTIC SYNDROME
COMPLICATED WITH RENAL VEIN THROMBOSIS IN CHILDREN
Yang D S, Han
ZM, Chen XD, Xing Y
The First Affiliated
Hospital, Xinxiang Medical College, Henan Weihui, China
Objective: To
study the association between white microthrombus, plasma D-dimer levels
and renal vein thrombosis (RVT) in nephroic syndrome (NS) patients.
Methods: 50
normal children were chosen as normal control group. 100 NS cases were
chosen. RVT can be diagnosed by continuous thin-layer reinforced helico-CT
for renal vein (thickness of CT-layer is 2 mm). 100 patients were divided
into two groups. The groupⅠ(n=88)
was NS patients without RVT and the groupⅡ(n=12)
was NS patients with RVT. White microthrombus were examined by WS-9 surface
microcirculation detector. Plasma D-Dimer levers were detected by ELISA.
Results: ① The positive rates
of white microthrombus in the groupⅡwas
much higher than that in the group Ⅰ(91.6%,
18.3%, p<0.005=.② The plasma D-dimer
levels were significantly higher in the group Ⅱ(2.06±0.57)mg/L than
that of the group Ⅰ(0.33±0.09)mg/L
and the normal control group(0.28±0.06)mg/L(p<0.01, p<0.001=, and that of the group Ⅰhad no difference
compared with that of the normal control group(p>0.05).
Conclusion:
In NS patients, positive white microthrombus and plasma D-dimer levels
increasing correlate closely with RVT.