Namazova A.A., Mustafayev Kh. D., Aliyeva A.I.

Azerbaijan Medical University, Baku, Azerbaijan


Brucellosis is a serious disease that is widely spreads among population of Azerbaijan in last years. Methods of effective treatment of chronic brucellosis of children are still uncompleted. The treatment of this disease includes antibiotics, sulfanilamide drugs, glucocorticosteroids and so on. But efficacy of this treatment is not satisfactory.

The goal of our research was working out the modern method of treatment of chronic brucellosis of children. 70 children (1-15 years old) with acute and chronic brucellosis were included in our research in 5 years. We diagnosed chronic brucellosis at 50 children, because since initiation of their disease passed more than 6 months. Diagnosis was proved by Rayt-Heddleson and Rozbengal tests. Titr 1:200 was considered as diagnostic criteria.

The treatment of 30 patients was widened by addition of biseptol in order to define its clinical efficacy. Biseptol was administered intra venosis in dosages 36 mg/kg in the haemodesum solution (polivinilpirrolidon). 20 patients (control group) didnít receive biseptol and were treated with antibiotics, immunoglobulin, vitamins.

5-year research shows that intoxication signs were significantly decreased at 30 patients whose treatment was widened with i/v infusion of biseptol. Weakness, muscle and joint pain, chill, and fever were decreased, appetite increased. We also noticed slowing-down of erythrocytes sedimentation rate, increase of Hb, erythrocytes, normalization of White Blood Count. Recurrence of chronic brucellosis at the patients treated with combination of antibiotics and biseptol were not observed.

Conclusion: The involvement of biseptol to the treatment of chronic brucellosis of children should be considered as reasonable and could be recommended for use in the clinics.