0234

VENTILATION AND VENTILATOR PNEUMONIA

Dong LJ, Ding FS, Wang SW, Li M

Harbin Children’s Hospital, Harbin, China

Objective: To explore the pathogenic factors and preventive and therapeutic measures of ventilator pneumonia (VAP).

Methods: In this group, 80 cases of patients were under ventilation treatment, there were 48 neonates among them. The mean ventilation duration was 241.3±46.1h, the longest was 1440 h (60d), and the shortest was 24 h. As soon as VAP took place, sensitive antibiotics were chosen, while large dose of immunoglobulin was applied in 28 cases.

Results: VAP took place in 56 cases among 80 cases, 6 cases died. The infection rate was 70.0% and the mortality rate was 10.7%.

Conclusions: 1. actors that could increase the infection rate listed below:(1) Transnasal endotracheal intubation; (2) upine position; (3)non-strictly sterilization of pipes 、humidifier or resuscitator of ventilator; (4) careless of washing hands of the medical staffs; (5) antibiotic abuse. 2. Most pathogen was resistant to antibiotics, but most of them were sensitive to the third generation of cephalosporin. 3. Large dose of immunoglobulin could prevent and cure VAP, and reduce its mortality rate.