0269

THE RELATIONSHIP BETWEEN THE HELICOBACTERIUM

PYLORIC INFECTION AND THE FUNCTIONAL DYSPEPSIA IN CHILDREN

ZHANG Wanming¹, WANG Lan², ZHENG Min²

1. Hubei Medical Staff College, Jingzhou, China

2. The Second Hospital of Jingzhou, China

Objective: To search for the relationship between the helicobacterium pyloric (HP) infection and the functional dyspepsia in children.

Methods: Case-control research. There were 163 cases of functional dyspepsia and 54 normal children in control group. The serum HP-IgC was determined by ELISA. The gastric urea test was used.

Results: The rate of the serum HP-IgG was 43.6% in the functional dyspepsia and 14.8% in normal children (X²=14.7, P<0.01). It was observed that the positive rate of the functional dyspepsia was higher than of the control group (15.3%:3.7%, X²=5.07, P<0.05).Among 15 cases of the functional dyspepsia examined with the endoscope, 12 cases suffered from chronic gastritis. The symptoms disappeared after antibiotics were used.

Conclusion: The functional dyspepsia is associated with infection of HP, which is a main etiological factor of the dyspepsia in children.