0294

THE EFFECTS OF THE ZINC SUPPLEMENTATION ON NUTRITIONAL STATUS OF PREGNANT WOMEN AND THE DEVELOPMENT OF THEIR FETUS

Xue M-B, Sheng X-Y, Hong Z-Y, Shen L-X, Zhu Z-B

XinHua Hospital Affiliated to Shanghai Second Medical University, Shanghai, China

Objective: To find out the effects of the zinc supplementation on nutritional status of pregnant women and the development of their fetus.

Methods: Forty-eight pregnant women were provided 20mg zinc daily from the second trimesters, the serum zinc’s concentrations of the mothers were measured in the second and third trimesters. The serum zinc concentration and the development parameters of the newborns were also measured. At the same time, compare those measurements with fifty-three other pregnant women who did not take any zinc supplementation, and their newborns.

Results: The serum zinc concentrations provided the pregnant women with more zinc than the control women in the final pregnancy stage (P<0.01). In those mothers who took the zinc supplementation, their newborns weighed significantly more than those newborns whose mothers did not take the zinc supplements (The serum zinc level in both were <10.71mmol/L) (P<0.05).

Conclusion: Zinc supplements could raise the serum zinc concentration of the pregnant women in their second and third trimesters. Zinc supplementation could also help to increase the newborn weight for those who had serum zinc <10.71mmol/L.

THE STUDY OF SENSORY INTEGRATIVE TRAINING IN CHILDREN WITH LEARNING DISABILITIES

Shen L-X, Zhang J-S, Xue M-B, Sheng X-Y, Jin X-M

XinHua Hospital Affiliated to Shanghai Second Medical University, Shanghai, China

Objective: To try to find a new way in treating children with learning disabilities.

Methods: We selected fifty female learning disabled children whose intelligence was normal in the clinic. They were aged from seven to ten. All of them were tested by sensory integration. Twenty-three children were sensory integrative dysfunction, and twenty-seven children were not sensory integrative dysfunction. Eleven of the twenty-three children who were sensory integrative dysfunction took the sensory integrative training, and the rest of them took Ritalin. Twelve of the twenty-seven children who were not sensory integrative dysfunction took the sensory integrative training, and the rest of them took Ritalin.

Result: 1.The children who were sensory integrative dysfunction: Eight of the eleven children who took the sensory integrative training learned better than before. Nine of the twelve children who took Ritalin learned better than before(X²=0.123, P)0.05).

2. The children who were not sensory integrative dysfunction: Four of the twelve children who were taken sensory integrative training learned better than before. Thirteen of the fifteen children who were taken drug therapy learned better than before (X²=6.01, P〈0.05〉.

Conclusion: 1. The effect of the sensory integrative training is just as well as drug therapy for the children who were sensory integrative dysfunction. 2. The effect of the sensory integrative training was not good enough than drug therapy for the children who were not sensory integrative dysfunction.

LOW DOSAGE ZINC SUPPLEMENTATION CAN INCREASE ZINC LEVEL AND IMMUNITY FUNCTION IN PRESCHOOL CHILDREN

Sheng X-Y, Xue M-B, Shen L-X, Hong Z-Y

Xinhua Hospital Affiliated to Shanghai Second Medical University, China

Objective: Evaluated the effect of zinc supplementation on children’s cell immunity function.

Methods: In a randomized, controlled trial in 143 preschool children (zinc, n=88, control, n=55). The daily dosage of zinc supplementation was 10mg of elemental zinc. In addition, we selected children whose serum zinc concentration lower than normal level in this 143 preschool children (zinc, n=25, control, n=15), and used the cytometry analysis the T lymphocytes in peripheral blood. Supplementation and surveillance were done for 6 months.

Results: After 6 months, the serum zinc concentration of zinc-supplemented children increased from 12.8±1.87mmol/L to 15.4±1.68mmol/L, (P<0.01), and higher than that of the control group, 14.4±1.20mmol/L, (P<0.01). At the same time, zinc-supplemented children’s CD4⁺T lymphocytes increased from 37.3±4.54 to 39.6±3.36，(P<0.01)，and CD8⁺ T lymphocytes from 26.7±5.07 to 28.2±4.66， (P<0.01). In surveillance period, there are no severe infections in zinc-supplemented children.

Conclusion: Low dosage of zinc supplementation not only increase the zinc concentration, but also improve immune status in zinc deficient children, and reduce the occurrence of the infection diseases.