0331
SERUM EOSINOPHIL CATIONIC PROTEIN ( E.C.P ) IN EVALUATION OF ASTHMA SEVERITY AND
DIFFERENTIATION BETWEEN ATOPIC
AND NON - ATOPIC VARIATIES IN CHILDREN Salam
T.H.1, EL-Gamal H.A2. 1 Clinical Pathology Department Ain Shams
University, Cairo, Egypt . 2 Institute of Post
-Graduate Childhood Studies, Ain Shams University, Cairo, Egypt. Objective:
To
Find out the value of serum ECP in the diagnosis of asthma, evaluation of
asthma severity and distinguishing between atopic and non atopic asthma. Methods: This study included 40 children their age ranged form 5-13 years (30 asthmatics and
10 healthy matched as a control group). All the children were subjected to
full history and clinical examination, complete blood picture, skin prick
test , IGE, CRP and serum ECP determination . Results: Serum ECP was significantly higher in asthmatic
group than control group (P> 0.01) While there was no statistical
significance between serum ECP in atopic and non atopic asthmatics also no significant
correlation between serum ECP and severity of asthma. Conclusion: Serum ECP may be useful as an
inflammatory marker in asthma.