THE
STUDY OF RELATIONSHIP BETWEEN BLOOD LEAD LEVEL AND CHILDREN’S IQ OF 96
CHILDREN IN CHENGGUAN DISTRICT OF LANZHOU
Duan Hongmei, Jin Yu, Wang Yuzhe, Xue Junli
First Affiliated Hospital, Lanzhou Medical College,
Lanzhou, China
Objective:
o estimate blood lead level and IQ sampled 96 children aged 4-6
years in Chengguan district of Lanzhou and to explore the relationship
between high lead level and IQ.
Methods: The lead level of capillary blood was
measured in 96 children aged 4-6 years by graphite stove atom absorption
spectrophotometry. Parents answered a questionnaire about family’s
socioeconomic and environment all variables. C-WYCSI Intelligence Scale
modified by Chinese researcher was used determined 96 children’s IQ.
Results: The mean blood lead level was
107.5ug/L (ranged from 88.6 ug/L to 248.5 ug/L). Standard deviation (SD)
was 36.3 ug/L. Blood lead level ≥100
ug/L was found in 49 from 96
children (51.1%) and there was a
significant negative correlation with IQ (r=-2.216, p<0.005). The concentration of blood lead level also have
relationship with socio-eco-nomic status, exposure to tobacco smoke and the
mother's education et al.
Conclusion: Lead is probably one of the risk
factors hindering mental development.
Keywords:
blood lead, mental development, IQ