HISTOLOGICAL CATEGORIES OF ASYMPTOMATIC HEMATURIA IN CHILDREN

Zhang guiju, Shen ying, zhang yuwen, et al

Beijing Children*s Hospital, Beijing, China

Objective: To study the kidney histological categories of asymptomatic hematuria in children.

Methods: 45 children with asymptomatic hematuria were given renal biopsy. All of them were examined by light microscopy, electron microscopy and immunofluorescence.

Results: Biopsies were classified as thin basement membrane nephropathy (TMN)(13), IgA nephropathy (11), mesangial proliferative glomerulonephritis(8), Alport syndrome(6), minor glomerular abnormalities (4), focal segmental glomerulosclerosis(4) and IgM nephropathy(1).

Conclusions: In this series the commonest biopsy diagenosis was TMN and Alport syndrome (42.2%), but a positive family history was observed in less than half. IgA nephropathy was the second most-frequent condition in the present series. There was a marked male predominance in IgA nephropathy. Some IgM nephropathy and focal segmental glomerulosclerosis may also present as asymptomatic hematuria.

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