CLINIC
APPLICATION OF MYOCARDIUM PERFUSION IMAGING AND GATED BLOOD POOL IMAGING IN
VIRUS MYOCARDITIS
Zheng
XQ, Zhang YX, Meng P, Gao ZR, Xu WD, Hu XH, He Y.
Department
of Pediatrics, Department of Nuclear Medicine, Union Hospital of Tongji
Medical College of HUST, Wuhan, China
Objective:
To study the value of myocardium perfusion imaging and gated blood
pool imaging for children virus myocarditis.
Methods:
99mTc-MIBI myocardium perfusion imaging were performed in 85
children patients to observe the blood perfusion of myocardium, including
59 patients those who performed 99mTc-RBC multiple gated blood pool imaging
at same time, to determine the systolic and diastolic function, phase
change of left and right ventricles.
Results:
Myocardial perfusion imaging results showed blood perfusion
decrease in anterior, inferior, posteriori, anteroseptal ventricle.The
rates are 76.5%, 34.1%, 20.0% and 17.6%, 78.8% in total . 59 cases gated
blood pool imaging results showed LVEF<50%, RVEF<40%, MFR<2.1,
MER<1.7 is 40.7%, 10.2%, 40.7%, 8.5%, phase shift >60o is 55.9%,
total abnormal rate is 74.6%.
Conclusion:
The study of children virus myocarditis examined by SPECT showed
anterior, inferior, posterior and anteroseptal perfusion defect in left
ventricle is most frequently, left heart function defects sometimes are
even worse than right heart, LVEF, MFR decrease and phase shift increase
are outstanding changes. Phase shift increase is the basic
pathophysiological change of myocarditis, positive rates are higher than
other imaging methods. Myocardium perfusion imaging and gated blood pool
imaging can provide the range of myocardium perfusion defect and degree of
heart function defect, so they can not be replaced by any other imaging
methods, especially for understand the range and degree of lesions in virus
myocarditis.