THE RELATION SHIP BETWEEN CARDIAC TROPONIN I LEVEL IN UMBILLICAL
CORD BLOOD AND ACUTE FETAL DISTRESS
Liu Manling, Ren Jiankang, Jiao
Fuyong, Kong Zhaohui
The Department of obstetric,
Sha’an XI provincial people’s Hospital Xi’an,
China
Objective: To detect
the CTnI level in umbillical artery and
study the relationship between CTnI level and acute fetal distress.
Methods: 94 neonates
and 30 of their mothers were enrolled in this study, including 20
newbornyinfants havingexperienced acute fetal distress and 14 asphyxied
neonates at birth. 94 specimens were taken from umbillical arteries and 30
were obtained from mother’s veins while delivery. CTnI levels were measured
by the chemiluminescnet immunoassay. Comparaison of CTnI level was made
between the normal and the acute fetal distress groups by student t test,
the analysis of factors affecting the CTnI level in umbillical cord blood
was performed by single and multiple correlation and regression methods.
Results: The CTnI
level in umbillical artery did not vary with the maternal venous blood
concentration and positively correlated with acute fetal distress (p<
0.05). The CTnI concentration
in cord blood of the acute fetal distress group (0.728±2.998 ng/ml)
was not only significantly higher than that of the normal group (0.024±0.183 ng/ml)
p<0.01 but also related to obstetric clinical characteristics of acute
fetal distress p< 0.05.
Conclusions: The CTnI
level reflected its concentration in fetus. The level was elevated in
neonates having experienced acute distress. It was an important index for
the diagnosis of fetal cardiac muscle injury.