Clinical features of Kawasaki
disease in different age group
Liao JX, Qiu BM, Yang
YP, Xia P, Li CG, Li CR
Shenzhen Children¡¯s
Hospital, Shenzhen, China 518026
Objective: To analyze
the clinical characteristics of Kawasaki disease.
Methods: Retrospectively
chart review of children with Kawasaki disease between 1997 and 2001.
Results: Of 61
patients, 16(22.54%) were less than one year of age (group A), 38(53.52%)
were more than one year of age but less than three years (group B),
14(19.72%) were more than three years of age but less than six(group C),
only two were more than six years of age(group D). Among these four age
group 10, 17, 4, and 2 developed coronary artery dilatation (CAD)
respectively. Compared with group C group A had significantly more patients
developed CAD(p£¼0.05). The total rate of CAD was 45%(30/71),
9(30%) of these developed CAD within seven days after the disease onset.
Treated with high dose intravenous immunoglobulin, only one patient
developed coronary aneurysms (CAA) by one month. There were altogether ten
cases whose manifestations were atypical, and no significant difference was
found among four groups.
Conclusions: CAD was a
major complication of Kawasaki disease, and infants less than one year of
age was more likely involved. High dose intravenous immunoglobulin therapy
could effectively prevented CAA.