SERUM LEVEL OF CATECHOLAMINE TRANSMITTER AND ACTION IN CHILDREN WITH SENSORY INTEGRATIVE DYSFUNCTION

Guo JH, Luo NP, Yang DL, et al.

Jinan Military General Hospital, Jinan, China

 

Objective: To investigate the correlation of serum level of catecholamine transmitter and action in children with sensory integrative dysfunction (SID).

Methods: The level of adrenlalin (A), noradrenalin (NE) and dopamine (DA) in 40 children with SID and 46 health children were quantitatively determined by radioimmunoassay (RIA). Attention defect. WAISC IQ, heart rate and the rate of studying difficulty were also measured.

Results: The level of A, NE and DA in SID group were [(0.64±0.19) nmol/L; (3.20±0.66) nmol/L; (1.45±0.20) nmol/L] respectively, which were significantly higher than in controls group [(0.52±0.10) nmol/L; (2.23±0.61) nmol/L; (1.31±0.18) nmol/L], (P<0.01, 0.010.05),  thenumber of attention defect, mean heart rate and the rate of learning disorder were significantly  higher  than that of normal children  (P<0.05, 0.01, 0.01), but there was no significant differences in IQ between two groups (P>0.05).

Conclusion: The higher serum level of A, NE and DA were presented in children with SID, and the abnormal changes were closely related to their sympathetic behaviors.

 
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