NEONATAL PERSISTENT PULMONARY HYPERTENSION REPORT OF
A CASE CONTROLLED WITH THIS MATERIAL (VIAGRA)
Honorio Santamaria-Diaz1, Alberto Orozco-Gutierrez2,
Rosa Maria Estrada2, Sergio Graham-Pontones2, Manuel
Gomez-Gomez2
1 Pediatric Cardiologist, Hospital Infantil Privado,2
Neonatologist, Departamento de Neonatología, Hospital Angeles del Pedregal,
Mexico, D.F., Mexico
The case of a newborn female product of
the first pregnancy of 26 weeks of gestation is presented, with respiratory
distress syndrome that required endotracheal intubation and mechanical
attendance to the ventilation soon after birth. To the fifth day she
presented data of cardiac insufficiency and patent ductus arteriosus,
without answer to indometacin IV for what to the eighth day surgical
closing is made. The ecocardiographic follow-up demonstrated persistent
pulmonary hypertension for what was done 21 days after birth inhaled nitric
oxid to 10 ppm, with good clinical answer although with reappearance of the
pulmonary hypertension to the retirement of this for what was administered
sildenafil to 1 mg/Kg/daily, every 12 hours, with what possible the prompt
decrease of the ventilatory parameters until decanullation 28 days after
birth. The after evolution was satisfactory with only treatment with
aminofilin and sildenafil, with 1950 g of weight to discharge, control of
temperature to the environment, spontaneous suction and progressive
increase of weight in spite of grade II bronchopulmonary displasia. In this
way is considered sildenafil (Viagra) an accessible alternative of handling
of persistent pulmonary hypertension of the neonate. Persistent pulmonary
hypertension; newborn; sildenafil.