CLINICAL STUDY OF THE EFFECTIVE OF CHUAN GONG QIN ON BLOOD-FAT AND APOLIPOPROTIN IN CHILDREN WITH NEPHROTIC SYNDROM

Yang Qiaozhi, Lu Xueyun, Yu Aiju, Liang Jun, Bu Yueqing, Wei Jinfeng

Department of Pediatrics, Liaocheng City People’s Hospital, Shandong, China

 

 

Objectives: To discuss the effective of chuangongqin on the blood-fat and Apolipoprotin In Children With Nephrotic Syndrom.

Methods: Thirteen four children who were suffered from nephrotic syndrome were randomized into two groups, control group (n=17)and study group (n=17) .All children were received conventional treatment. At same time, study group were also received large-dose chuangongqin intravenous injection. The fasting intravenous blood was collected before and after treatment 2 weeks. Blood-fat and apolipoprotin were tested using OLYmpus AU640 total blood biochemical.automatic instruments.

Results: After treatment the serum total cholesterol (STC), Triglceride (TC0), low density lipoprotin cholesterol (LDL-C), very LDL-C (VLDL-C), apolipoprotinB (apoB) were significant decreased, high density lipoprotin cholesterol (HDL-C), apoA1 were significant increased (p<0.01). To comparative with control group, TC, LDL-C, VLDL-C, apoB were very significant decreased (p<0.01) and HDL-C, apoA1 were very significant increased (p<0.05) in study group. There were significantly differences in two groups. No side effective occurrences in study group.

CONCLUSIONS

Using large-dose chuangongqin treatment fat metabolic disturbance which due to hormone therapy in children with nephrotic syndrome is an effectve methond which have safe and economy.

 

 

 
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