THE LEVELS OF PLASMA LIPIDS IN CHILDREN WITH FAMILY OF CORONARY HEART DISEASE

Xiang W1, Zhao S-P2, Zheng C1

1 The people¡¯s Hospital of Hainan Province, Haikou, Hainan Province, China

2 The Second Affiliated Hospital of Hunan Medical University, Changsha, Hunan Province, China

 

Objective: In order to investigated the level of plasma lipid, lipoprotein, apolipoprotein (apo) in children with family of coronary heart disease (CHD).

Methods: The concentrations of plasma lipids were determined between  83 children with family of CHD and 83 normal controls.

Results: Compared with control group, the levels of  triglyceride, total  cholesterol, low density lipoprotein-cholesterol, apoB100, lipoprotein (a) were higher , high density lipoprotein- cholesterol, apoA I, apoE were lower in children with family of CHD (P<0.05). There were no significant statistically in blood lipids between boys and girls in children with family of coronary heart disease. Compared with family of nonpremature CHD, there had more significant lipids metabolism abnormalities in children with family of premature CHD. When these items were applied to discriminate whether there parents got CHD or not, a very high positive rate were found, it was more apparently in premature CHD.

Conclusion: There is abnormality of lipids metabolism in children with the family of CHD .It is significant in children with family of premature CHD.

 
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