THE USING OF IMMUNEMODULATOR THYMALIN WITH PATHOLOGY OF CHILDREN¡¯S THYMUS

Huseinov Sh., Hasanova G.

Medical University, Baku, Azerbaijan

 

Thymomegaly is one of the most spreaded pathology of children¡¯s thymus, it causes for death and is the precede factor of pneumonia.

Objective: There was done the clinical- rontgenological and laboratory research of 68 children with thymomegaly complicated sharp pneumonia. Besides generally accepted treatment, to 34 of them was used the immunemodulator of thymus-thymalin -with the dose 0.2mg/ kg in 24 hours intramuscular per day during 5-10 days.

Methods: The functional condition of thymus and hypophysis-adrenal system was evaluated by the content of indexes of T and B immunity system adrenocortropine hormone (ACTH) and cortisole.

Results: At the children with thymomegaly complicated pneumonia, treated by thymalin, the improvement of clinical currency of disease is noted. It was observed the clinical recovery in 12-14 days, that means faster in two times than without thymalin using.

Conclusion: The comparison of immune and hormone statuses¡¯ parameters and clinical- rontgenological view in the dynamic of disease indicated that children with the thymomegaly, treated by thymalin, with the normalization of immunity and adrenocortical system¡¯s indicators, the clinical -rontgenological involution of thymus observed. And also the cardiorespiratoral and circular complications are taken faster, the exacerbation and additional after-effect of the illness is not mentioned.

 
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