the risk factors of status epilepticus in children

Wang Yi, Zhang Jin, Sun Daokai

Children’ s Hospital of Fudan University, Shanghai, China

 

Objective: To investigate the risk factors of status epilepticus (SE) in children.

Methods: Case-control study conducted on 77 patients with SE and 154 controls with epilepsy but non-SE. Conditional Logistic regression analysis was undertaken. Twenty-four variables were analyzed.

Results: Ten factors (including certain etiology, seizure as SE before, with retractable seizure, the seizure type were complex partial or partial secondary to the generalized seizure or atypical absence, abnormal neurological image, abnormal background or focal spike in EEG, and non-compliance with antiepileptic drugs were related to SE following single-factor analysis. By the multiple factor analysis, the main risk factors were isolated certain etiology (OR=5.62), seizure as SE before(OR=4.50), complex partial (OR=2.96) or partial secondary to the generalized seizure OR=2.40, abnormal background in EEG (OR=2.06) and non-compliance with antiepileptic drugs (OR=1.72). 

Conclusion: SE is affected by the six factors, which are indicators of a higher risk of SE in children.

 

 
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