PRELIMINARY
STUDY OF UMBILICAL SERUM LEPTIN IN NEONATES
Wei Chaoping, Huang Yonglan, Liu Yunke,
et al.
Women and Children’s Hospital of
Guangzhou, Guangzhou, China
Objective: To study influencing factors of umbilical serum leptin level.
Methods: The concentration of cord serum leptin was detected by ELISA
in 46 neonates (female17, male 29; pregnant age 31-41 weeks; body weight
1.6-3.8Kg). The body lengths, weights, body mass indexes (BMI) of neonates
and placental weights were measured. Correlative analysis was done between
umbilical serum leptin level and pregnant age, body weight, length, BMI of
neonate, placental weight. Meanwhile comparison of serum leptin level was
carried out in different birth time phases (8:00-20:00 vs 20:00-8:00) and
gender.
Result: The umbilical serum leptin level was
significantly correlated to pregnant age (r=0.409, p<0.01), body weight
(r=0.463, P<0.01), body length (r=0.358, P<0.05), BMI of neonate
(r=0.328, P<0.05) and placental weight (r=0.363, P<0.05). There are no
significant differences in birth time phases and gender, although the level
of cord serum leptin is higher in girls than in boys (8.87±13.15ng/ml vs 7.43±10.03ng/ml).
Conclusion: The level of cord serum leptin is significantly correlated to
pregnant age, body weight, BMI of neonate and placenta weight; It dose not
show a diurnal rhythmic descending trend and bisexual difference.