文本框: CHANGES OF CEREBRAL GLUCOSE METABOLISM BY FDG PET IN CHILDREN WITH INTERICTAL OR TERICTAL EPILEPSY Zhai Q-X, Lin X-Y, Zhang Y-X, Qiao Z-X Department of Pediatrics, Guangdong Provincial People’s Hospital, Guangzhou, China Objective: To assess the diagnostic value of 18F-FDG imaging for interictal and terictal epileptic foci. Methods: 23 patients with epilepsy were examined in the interictally and terictally by 18F-FDG PET, the results of examination have been compared with MRI and EEG. The patients are 10 cases in male, 13 cases in female. The youngest is 3 day old, the oldest is 14 years old. Result: There are some abnormal metabolism focuses on PET imaging in 21(91.3%) patients with epilepsy. Lower metabolism focus is in 19 cases, higher metabolism focus is in 2 cases. 2 case is in normal. One case of two with higher metabolism focus is attack during the examination. Before examination in three hours there is an epileptic attack in other one case. The epileptic focus had been moved by operation in another two cases. It has been found that the location of focus is the same with the abnormal metabolism focus from PET. Younger children with epilepsy, their abnormal metabolism focus is much more than elder children. MRI is abnormal in 69%, EEG is abnormal in 86%. Conclusions: The diagnostic value of 18F-FDG PET imaging for interictal or terictal epileptic foci was higher than that of MRI and EEG in sensitivity. The possible seizure episodes the specificity and accuracy of 18F-FDG PET imaging for the diagnosis of epilepsy could be even better elevated. 0684