文本框: ANLYSIS OF A FIVE-YEAR FOLLOW-UP STUDY IN CHILDREN WITH COUGH VARIANT ASTHMA Wu Shuyue, Pan Ge, Su Huixian, Li Huiling, Zhong Wei The 3rd Affiliated Hospital of Guangxi Medical University, Nanning, China Objective: To explore the best therapy for cough variant asthma and to evaluate its curative effects by analyzing a five-year follow-up study in 60 children with such disease. Methods: The sick children were randomly divided into two groups: Group A treated with glucocorticoid inhalants and Group B with immuno-regulatory agents. The curative effects, medical expenses and parents’loss of working time were observed. Results: (1) The therapeutic effect in Group A was better than that in Group B.(U=5.1389, P＜0.001). (2) Asthma occurrence was 26.7% (8/30) in Group A and 63.3% (19/30) in Group B (3) The PEFR in Group A was better than that in Group B. (4) There were statistically significant differences in medical expenses and parents’loss of working time before and after treatment in Group A (P＜0.001) and no significant differences in Group B(P＞0.05). Conclusion: Early intervention treatment of cough variant asthma with glucocorticoid inhalants can protect the sick children’s pulmonary function, reduce medical expenses and parents’loss of working time and especially improve life quality. 0747