文本框: DIAGDOSIS AND THERAPY OF UNDIFFERENTIATED JUVENILE SPONDYLOARTHROPATHY (JUSpA) Yao Y, Ma SC, Chen F Beijing Children’s Hospital, Capital University of Medical Science, Beijing, China Objective: To explore diagnosis and prognosis of JUSpA, strengthen understanding of this disease and put forward the importance of early diagnosis and therapy. Methods: A retrospective study was performed in this hospital on 94 inpatients according with Amor’s standard. 82 of them were followed up during 2- 12 years. Result: The male to female ratio was 10:1 in 94 patients. The average age was10.4 years and the average course were 2.6 years. The first symptom was lumbago (32%), low extreme joints (63%) and achilles tendinitis (3.2%) respectively. Iridocyclitis was found in 2 caseas (2.1%). Doubtful sacroiliitis (≤II grade) was presented by radiography in 19 cases (23.1%). Sacroiliitis occurred in 2 of 13 sacroiliac CT (15.5%). ANA and RF were negative of all. HLA-B27 was positive in 78 cases (83.3%). All the patients were treated with NSAID and SASP. The total effective rate was 82%. The follow-up results of 82 cases showed that 18 cases were cured (21.9%), 21 cases were remitted (25.6%), 50 cases (60.9%) still had arthritis, Joint malformation was found in 12 cases(14.6%).35 patients had developed to JAS in the end. Among them, 23 patients could be diagnosed as JAS (28.1%), 12 patients were highly suspected as JAS. Conclusion: JSpA is a group of chronic arthritis and different form JRA. Pauciarticular disease type II should belong to JSpA, then should be called JUSpA.SASP was main medicine in treatment. The patients should be followed up for a long time and reexmined by sacroiliac X-ray, CT in time. Then they will be diagnosed and treated earlier. 0749