文本框: PULMONARY FUNCTION EXAMINATION OF TODDLER CHILDREN WITH ASTHMA
Deng L, Ye Q-C, Jiang W-H, et al
Respiratory Department of Guangzhou Children’s Hospital, China

Objective: To disclose the changings rules of pulmonary function in toddler children with asthma in acute exacerbation stage and relaxing stage.
Methods: The pulmonary function of 81 toddlre children who with asthma were measured with use of tidal flow volume curve, passive expiretory flow volume techniques, open. Nitrogen washout method in their exacerbation stage, in which 34 of the 81 children’s pulmonary function were also measured in their relaxing stage, and 54 normal children were same as the control group.
Indexes of Tidal Volume/kg (Tv/kg) and Respiratoy Rate (RR) are strowing small airway function, which are significantly different in exacerbation stage and relaxing stage (p<0.001). Same difference are also seen in tidal expiratory flow 50%/ tidal inspiratory flow 50% (ME/MI) and Functional Residual Capacity/kg (FRC/kg). It mainly showed large airway function (p<0.05). When the values of pulmonary function of 81 asthmatic infants were compared with that of 54 normal infants, %Volume to Peak Tidal Expiratory Flow (%V-PF), Expiratory Flow at 75% of tidal volume to Peak Tidal Expiratory Flow (25/PF)(p<0.001) and ME/MI(p<0.03) are significantly different. But still significant difference are noticed of % Inspiratory Time (Ti/Tt) and ME/MI (p<0.01) between 34 relaxing stage asthmatic infants and normal 54 ones.
Conclusion: %V-PF and 25/PF are sensitive indexes showing small airway function, while ME/MI is sensitive showing large airway function.still some indexes appears abnormal in relaxing stage. That suggests long-term treatment is necessary.
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