文本框: RELATIONSHIP BETWEEN UMBILICAL LEAD LEVEL AND NEONATAL PHYSICAL GROWTH AND DEVELOPMENT IN HAN AND UYGUR  
Li W-CH, Li M-X   
First Affiliated Hospital of XinJiang Medical University, China 

Objective: To study the effects of intrauterine low levels lead exposure on neonatal physical growth and development.
Methods: Maternal and umbilical blood lead level and indicators for physical growth and development were determined in 139 cases of neonates (80 cases of Han and 59 cases of Uygur) from March to September, 2000.
Results: (1) Among the 139 cases, maternal blood lead level were12~267(84.91+47.
46) μg/L, Umbilical blood lead level were 10~329(65.08+43.88) μg/L. There was significant statistical correlation between maternal and umbilical blood lead levels (r=0.7140, 0.7898, p<0.01). Maternal and umbilical blood lead levels were higher in Uygur than that of Han (p<0.01, p<0.05). The blood lead level was≥100μg/L in 54 cases of  pregnant women and 49 cases of neonates.  (2) The umbilical blood lead level correlated in reverse to neonatal body height, weight and head circumference (p<0.01). And they were obv-iously lower in neonates with umbilical blood lead level greater than or equal to 100μg/L than that of the neonates with umbilical bloodlead levels less than 100μg/L (p<0.01). But there were no significant association between umbilical blood lead level and neonatal chest measurement and left upper arm circum-ference (p>0.05).
Conclusions: Intrauterine low levels lead exposure could cause adverse effects on neonatal physical growth and development. Neonatal lead poisoning in Urumqi was relevant higher. Enough attention should be paid to the situation.
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