COMPARISON BETWEEN TWO KINDS OF
PULMONARY FUNCTION MEASUREMENTS IN CHILDREN WITH ASTHMA
Li Shuo, Song X, Cao L, Chen
YZ.
Capital Institute of Pediatrics, Beijing, China
Objective:
The relationship between Flow-volume (F-V) and Impulse oscillation (IOS)
airway resistance was evaluated through simultaneous measurements of them
in 50 asthma children. The determination of the IOS measurement and its
clinical application were discussed.
Methods: The
F-V and IOS airway resistance was determined by means of Jaeger Mastscreen.
Before and after the bronchodilator provoking test. The measurement data
were analyzed by comparing the indexes, viz.: first second expired volume
(FEV1), forced vital capacity (FVC), maximum mid-expiratory flow
(MMEF), respiratory resistance (Zrs), total airway resistance (R5), central
airway resistance (R20), periphery resistance (X5) ，frequency of response (Fres).
Results: The
results showed that after bronchodilatation, FEV1, MMEF and FVC
were significantly increased as compared with the baseline, while Fres,
Zrs, R5 and X5 were apparently reduced (p< 0.01). There is a good
correlation between FEV1, MMEF, FVC and Fres, Zrs, R5, R20, X5
of the baseline and those after bronchodilator challenge. Comparing the
degree of severity in FEV1 with IOS, it was noticed that when
FEV1>80%, R5 and
X5 had already increased slightly. It indicated that IOS measurement was
more sensitive.
Conclusion:
Since IOS is simple to be performed, it’s suitable for children, especially
the per-school children. Thus IOS measurement widens the application of
pulmonary measurement.