FACTORS INFLUENCING RESULT OF PBPV AND LONG-TIME FOLLOW-UP

Xia W, Yang XJ, Wang YW, Zhao CF, et al

Qilu Hospital of Shandong University, Jinan, China

 

Objective: To discuss the influencing factors of percutaneous balloon pulmonary valvuloplasty (PBPV) and the changes of cardiac morphology after PBPV.

Methods: Multiple linear regression was adopted to studying peak gradient, balloon-anulus ratio(BAR), pulmonary orifice area and time of inflation before and after PBPV. T test was adopted to studying diameter of right ventricular (RV), thickness of RV and Rv1 of EKG before and follow-up. F test was applied to determine peak gradient of before, after PBPV and follow-up.

Result: 82 patients (age between 10months and 28 years, mean 8.25±0.62). There was a resultant reduction in the peak to peak gradient from 12.34±0.73 kPa to 4.79±0.36 kPa (p<0.001). Clinical and Doppler follow-up of 87±26.3 (38 to 126) months after PBPV was obtained in 42 patients and a further decrease in the gradient was noted, to 3.73±0.42 kPa (p0.001). Diameter of RV, thickness of RV and Rv1 of EKG have gotten good changes(p0.05). Obtained regression equation. A=13.46+0.3208X-6.9626Y-0.7535Z (A resdue gradient after PBPV; X peak gradient before PBPV; Y balloon-anulus ratio; Z pulmonary orifice area.), R2=0.6506.

Conclusion: Patient’s condition of pulmonary valve stenosis(PVS) is key fact influencing result of PBPV; proper BAR is a preparative condition; the results of late follow-up of PBPV are excellent. Cardiac good changes in morphology after PBPV have acquired in low-age children more than high-age patients. It is suggested that PVS had been diagnosed, the patient should be treated with PBPV at once.

 

 
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