THE STUDY OF THE CLASSIFICATION OF THE ROTAVIRUS OF THE INFANTS’ DIARRHEA IN CHANGCHUN REGION

Wang CX, LiuY, Sun LW, Tutor Fang ZY*

Changchun Children’s Hospital, Jilin, China  

*Institute of Virology, Chinese Academy of Preventive Medicine

 

Objective: To study the epidemic regularity of the blood serum type of rotavirus.

Methods: The comparative study using the methods of PAGE, ELISA and RT-PCD in testing HRV.

Results: According to the differences of Vp4  alnumen in the virus shell and antigenicity ,the rotaviruses are divided into the following types: P (VP4Proteas, sensitive) and G (Vp7,Glycoprotein). In the experiment, the selection of the non-bacteria diarrhea samples of 238 case of the acute diarrhea of the infants has been done in ChangChun region. The result is that there is 110 positive samples (46.2%). The long electrophoresis type ranks the first (91.8%). The G-classification has been carried out though the MABELISA and RT-PCR of the special case, the result shows that from 1998-1999,in the epidemic season of HRV, typeG1 remains the main epidemic disease, with the total amount of (91.8%). The subsequent is G3 (4.5%)G4 (2.9%) G2 (0.9%).In addition, there are 4 cases of HRV which could not be classified and there are 5 cases which are the mixed infection .This paper discusses the epidemic regularity of the blood serum type of HRVG.

Conclusion: Form 1998-1999, in the epidemic season of HRV typeG1 remains the main epidemic disease in ChangChun region.

 

 
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