文本框: THE ANALYSIS OF CLINICAL SIGNIFICANCE OF RAPID QUANTITY OF CRP IN UPPER RESPIYATORY INFECTION
Wang M-Y,Yang L-Q, Ge M, Shen D-W, Mu C-S
Jinan Railway Central Hospital, Jinan, China

Objective: To study the significance of rapid quantity of CRP in differential diagnosis of the upper respiratory infection(URI)which was caused by bacteria or virus in children. 
Methods: 263 cases with URI were divided into two groups at random, Quick-Read CRP apparatus detecting CRP and blood routine tests were done in test group. The cases were treated with antibiotics when  CRP≥10mg·L-1, otherwise were treated with antivirotics when CRP <10mg·L-1; Only blood routine tests were done in control group. The cases were treated with antibiotics when WBC≥10×109 L-1, otherwise were treated with antivirotics when WBC <10×109 L-1. The cases whose temperature declined to normal after 3 days' treatment were recorded.  
Results: The number of cases whose temperature declined to normal after 3 days' treatment was respectively: 122 (76.3%) in test group, 50 (48.5%) in control group, p<0.001. The number of cases whose temperature declined to normal after 3 days' treatment with antibiotics was respectively: 40/52 (76.9%) in test group, 21/48 (43.7%) in control group, p<0.01. And those after 3 days' treatment with antivirotics was respectively: 80/108 (74.1%) in test group, 39/55 (70.9%) in control group, p>0.05.     
Conclusion: The efficiency of antibiotic therapy based on the quantity of CRP is higher than that based on WBC. Because WBC may rise slightly at the initial stage of some viral infection and be mistaken as bacterial infection. Rapid quantity of CRP is reliable to determine the cause of upper respiratory infection. 


    

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