TRADITIONAL CHINESE MEDICINAL HERBS “WEI PING”GRANULE TREAT PEPTIC ULCERS IN CHILDREN

Chen Zh-D, Yan H-M, Li S–T, Yan R-J, Hou L-Y

Beijing Children’s Hospital, Beijing, China

 

Objective: To evaluate the therapeutic effect of “Wei Ping” granule in peptic ulcers with children.

Methods: All 98 children with peptic ulcers confirmed by flexible gastroscopy in Beijing Children’s Hospital between June 1992 and December 1997. Detected Helicobacter pyloric (Hp) used rapid urease testing (RUT) on gastric biopsy and biopsy specimens with Giemsa stain. All patients took “Wei Ping” granule orally over 4 weeks. After the therapy observe the symptoms and physical signs to evaluate the curative effect. 65 children were rechecked by gastroscopy, 76 children were followed-up after discharge.

Result: 98 children (79 children with duodenal ulcers, 19 children with gastric ulcers) were surveyed in this study. The clinical cure rate was 55.1%(54/98); improvement rate was 39.8%(39/98); ineffective rate was 5.1%(5/98); Total effective rate was 94.9%. To evaluate the curative effect through gastroscopy: cure rate was 83.1%(54/65); improvement rate was 12.3%(8/65); ineffective rate was 4.6%(3/65); Total effective rate was 95.4%. The positive rate of Hp in peptic ulcers was 56.1%(55/98). After therapy Hp eradication rate was 63.6%(35/55). 76 children were followed-up after discharge, follow-up survey rate was 76.5%. Peptic ulcers recurrence rate was 25.0%(19/76).

Conclusions: Traditional Chinese Medicine “Wei ping’’ granule improve the curative effect and get lower recurrence rate in peptic ulcers.

 
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