文本框: CLINICAL VALEU OF MEDIAN NERVE SOMATOSENSORY EVOKED POTENTIALS IN HIGH-RISK NEONATES Chen Q, Xu KM Capital Institute of Pediatrics, Beijing, China Objective: To observe the clinical value of median nerve somatosensory evoked potentials (MNSEP) in high-risk neonates. Methods: MNSEP were measured by using NOMAD-3400 neurodiagnosis system. MNSEP, physical and mental development of 30 infants with high-risk factors were longitudinally studied in neonatal period,6 and 12 months of age. Results: The central conduction time (CCT) recorded from high-risk neonates was longer than that of healthy neonates, p<0.01,but the peripheral conduction time (PCT) recorded from the two groups had no significant difference (p>0.05). All cortical potentials N20 were recorded from 60 sides in 30 healthy neonates, however, only 48 waves were obtained in noenates with high-risk factors. The rate of abnormality in neonatal period was obviously higher than that in 12 months of age, p<0.05. 30 subjects were examined at 12 months of age, 23 cases developed normal, the rest 7 cases suffered from various neurological sequelaes, whose MNSEP showed continuously abnormal at all period. Conclusion: In high-risk neonates, was found abnormal MNSEP, expressed as increasing CCT, absence of the wave N20 in one or both sides. MNSEP is a non-invase, safe, sensitive and economic supplementary method, can be used to monitor patient’s condition and predict the prognosis in the infants with high-risk factors. 0963