文本框: MEASUREMENT OF SERUM TUMOR NECROSIS FACTOR-2 AND INTERLEUKIN-8 IN CHILDREN WITH LOW RESPIRATORY TRACT INFECTION (LRTI) CAUSED BY MYCOPLASMA PNEUMONIA Che L, Lu J, Lu J et al Capital Institute of Pediatrics, Beijing, China Objective: To investigate the immuno-pathological mechanism of LRTI caused by mycoplasma pneumonia. Methods: Serum tumor necrosis factor-2 (TNF-2) and interleukin-8 (IL-8) from 30 patients with LRTI caused by mycoplasma pneumonia and healing controls were measured with sequeme saturated solution competitive radio-immunoassay and sandwich ELISA. The age rang was 3~10yrs (median 5yrs). Results: The levels of serum TNF-2 and IL-8 of patients suffering from LRTI caused by mycoplasma pneumonia were magnificently higher than that of healthy children. Meanwhile, a positive correlation between serum TNF-2and IL-8 was noticed. Serum TNF-2 and IL-8 levels in seven cases were obviously higher than that of mild cases. Conclusion: TNF-2plays an important role in LRTI caused by mycoplasma pneumonia, and serves the key factor to the elevation of IL-8. 0967