CHANGE ON NO IN PULMONARY HYPERTENSION IN CHD WITH SHUNTS FROM LEFT
TO RIGHT
Chu Maoping, Chen Qi, Lu Wenwen, et al.
Children's
Hospital of Wenzhou Medical College, Wenzhou, China
Objective: To explore the clinic value on Nitrogen monoxide (NO) in pulmonary
hypertension in congenital heart disease (CHD) with shunts from left to
right.
Methods: ⑴ To detect the
pulmonary artery(PA) pressure in CHD, divide the patients with CHD into the
pulmonary
hypertension (PH) group (n=52) and the non pulmonary hypertension (NPH) group(n=11);⑵The concentrations of NO were measured
in superior vena cava (SVC) and PA in the PH group and the NPH group, also
in the vein in the control group(n=25).
Results: ⑴There were significant
differences between the PH group and the NPH group, the control group,
there was no significant difference between the NPH group and the control
group; ⑵There were significant
differences between the any two groups in the mild PH group, the mid-degree
PH group and the severe PH group.
Conclusion： There
was a close correlation between the change of the level of NO and
pneumoangiogram lesion, detecting the serum level of NO can estimate the
degree of pulmonary hypertension in congenital heart disease.