文本框: ASSESSMENT FOR VENTRICULAR FUNCTION ON VMC TREATED WITH CAPTOPRIL IN PEDIATRICS
XIANG Rulian, CHU Maoping, WU Rongzhou, et al
Children's Hospital of Wenzhou Medical College, Wenzhou, China
 
Objective: To explore the clinic assessment for ventricular function before and after treatment with captopril on viral myocarditis (VMC) in children. 
Methods: Contractive and diastolic function of cardiac ventricle were detected by doppler echocardiography in the VMC group (n=60) and the control group (n=30); The VMC group was divided into group A and B in random [group A treated with captopril (n=30) and group B treated with the routine therapy (n=30)], and detecting the contractive and diastolic function after treatment. 
Results: ⑴ The contractive and diastolic function obviously declined in children with acute VMC, there was a significant difference between the VMC group and the control group (p<0.01); ⑵ In group A the contractive and diastolic function obviously ameliorated after treatment (p<0.001), In  group B the contractive function improved (p<0.01) but the diastolic function didn’t take a turn for the better (p>0.05); The effect after treatment of group A was better than group B.
Conclusions: ⑴ There were decrements of the contractive and diastolic function in acute viral myocarditis; ⑵ It was a effective therapy that the patients were treated with captopril in acute VMC, was worth extending in clinic.

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