0P-S6-3

CURRENT STATUS OF LIVE RELATED LIVER TRANSPLANT IN CHILDREN AT THE UNIVERSITY OF TOKYO

Kawarasaki H¹, Mizuta K¹, Hashizume K² and Makuuchi M²

¹ Jichi Medical School, Tochigi, Japan

² The University of Tokyo, Tokyo, Japan

Between January 1996 and March 2001, live related liver transplantation (LRLT) has been performed 67 times in 65 children under 18 years old. Indication for LRLT is biliary atresia in 59 (91%), Alagille Syndrome in 2 (3%), Wilson’s Disease in 2 (3%) and liver cirrhosis associated with hepatectomy for hepatoblastoma in 2 (3%). Donors are mother in 34 (51%), father in 29 (43%), grandmother in 2 (3%), uncle and aunt each in 1 (1.5%). Hepatic artery thrombosis has been associated in 9 (13%), bowel perforation in 8 (12%) and bile leakage in 10 (15%). Acute rejection has been found in 35%. Six children died and 59 (90%) are surviving and enjoying normal daily life. Major post-operative complication has not been observed in donors and all of donors are surviving and doing well.