Text Box: THE PAIRING ANALYSIS AND CLINICAL MEANING OF sICAM-1, NO, CKs AND PEF IN THE SERUM OF ASTHMATIC CHILDREN BEFORE AND AFTER THEY HAVE INHALED HORMONE
Feng YZ, Sun ZH, Cui AH
Department of Pediatrics, Shandong Provincial Hospital, Jinan, China

Objectives: Exploring the variations of sICAM-1, NO, CKs and PEF in the Serum of asthmatic Children before and after they have inhaled hormone and their clinical significance.
Methods: 12 asthmatic children were selected and their empty-stomach venous blood samples were taken before and after they had inhaled hormone and been controlled. The double antibody sandwich ELISA method is used to test sICAM-1, TNF-¦Á and IFN-r, and the nitric acid deoxidized enzyme for NO and the micro peak flow instrument for PEF. At last, the pairing analysis is completed with the T checkout.
Results: sICAM-1. NO and TNF-¦Á are respectively 306. 12¡À48. 10¦Ìg/L. 152. 70¡À37. 13¦Ìmol/L and 12.34¡À7.92ng/L during the active period, and they are significantly higher than those figures during the controlled period (They are respectively 223. 67¡À40.65¦Ìg/L, 109.60¡À25.23¦Ìmol/L and 7.97¡À3.89ng/L, P<0.01 and 0.05). To mention IFN-r and PEF, they are respectively 3.42¡À2.34ng/L and 165.0¡À5.29L/min during the active period, and significantly lower compared with 7.56¡À3.25ng/L and 221.0¡À61.86 L/min during the controlled period and p is less than 0.01.
Conclusions: In-haling hormone has an affirmative effect on asthmatic patients through adjusting the balance of sICAM-1 and CKs at human bodies.
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