VALUE AND APPLICABILITY OF TIDAL BREATHING FLOW VOLUME CURVE IN ASSESSMENT OF AIRFLOW OBSTRUCTION IN BABIES WITH BRONCHIOLITIS

Cui ZZ, Li XH, Fang F, Ma XH, Cao CJ

Dalian Children's Hospital, Dalian, China

Objective: To evaluate the value and applicability of tidal breathing flow volume curve (TBFV) expressed as TV/Kg, %V-PF, 25/PF, PF/Ve, ME/MI, Crs, Rrs in assessing airflow obstruction in babies with bronchiolitis, and those parameters’ relativity with PCO₂ or PO_{2 .}

Methods：The authors measured TBFV in 31 babies with bronchiolitis and 30 healthy babies, while measured blood analysis in babies with bronchiolitis with distal blood which was arterialized.

Results：In babies with bronchiolitis, the mean TV/Kg, %V-PF, 25/PF, PF/Ve, ME/MI, Crs, Rrs separately were 6.49±1.52 ml, 0.14±0.08, 0.37±0.16, 2.15±0.58 0.50±0.07, 1.32±0.16, 0.007 ± 0.002, which were significantly change as compared with healthy subjects（8.43±1.31ml, 0.29±0.14, 0.69±0.10, 1.49±0.40, 0.93±0.04, 1.32±0.45, 0.04±0.01, P<0.01) except Crs, Rrs. There was a positive correlation between PCO₂ and Rrs（r = 0.45, P<0.05)；or between PO₂ and TV/Kg or Crs（r =0.39 ,P<0.05；0.52, P<0.01).

Conclusions：TBFV’s parameters TV/Kg, %V-PF, 25/PF, PF/Ve, ME/MI could reflect the airflow obstruction in babies with bronchiolitis, and there was a lower positive correlation between PCO₂ and Rrs or PO₂ and TV/Kg, a significant correlation between PO₂ and Crs.

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