VISUAL, AUDITORY AND EVENT RELATED POTENTIALS (P300) IN DIABETIC CHILDREN

Fardus H. Abdel Hafez, Wafaa M.A.Farghaly*, Hamdy N. A. Elallawy*, and Hind S. Thabet**

Pediatric Department, Neurology Department*, and Pediatric nursing**

Assiut University, Assiut, Egypt

 

Objective: Neurophysiological changes are commonly associated with Diabetes, and sometimes precede the manifest diabetes. Most of neurophysiological studies deal with distal latency, conduction velocity (sensory & motor) and somatosensory evoked potentials. Neurophysiological changes in the brain stem and cortex are not fully evaluated. This study was designed to illustrate if there is visual, auditory and event related potentials (P300) changes among diabetic children, and it is related whether to duration and /or degree of affection, and to detect these changes even before clinical manifestations appear.

Methods: Twenty children with diabetes of both sex and different duration were subjected to full clinical examination, visual, auditory as well as event-related potentials (P300).

Results: The results of the study clarified that abnormal visual and auditory evoked potentials were recorded in diabetic children.  Meanwhile, abnormal (P300) latency was recorded in 47.6% of diabetic children.

Conclusion: This study clarified that peripheral as well as central nervous system abnormalities are commonly observed in diabetic patients irrespective of type of diabetes, severity and treatment. And these abnormalities may be detected even before clinical manifestations appear. So that, early control of diabetes may help to prevent the progress of these changes.  

 

 
1170