VISUAL, AUDITORY AND EVENT RELATED POTENTIALS (P300)
IN DIABETIC CHILDREN
Fardus
H. Abdel Hafez, Wafaa
M.A.Farghaly*, Hamdy N. A. Elallawy*, and Hind S.
Thabet**
Pediatric Department, Neurology
Department*, and Pediatric nursing**
Assiut
University, Assiut, Egypt
Objective:
Neurophysiological changes are commonly associated with Diabetes, and
sometimes precede the manifest diabetes. Most of neurophysiological studies
deal with distal latency, conduction velocity (sensory & motor) and
somatosensory evoked potentials. Neurophysiological changes in the brain
stem and cortex are not fully evaluated. This study was designed to
illustrate if there is visual, auditory and event related potentials (P300)
changes among diabetic children, and it is related whether to duration and
/or degree of affection, and to detect these changes even before clinical
manifestations appear.
Methods:
Twenty children with diabetes of both sex and different duration were
subjected to full clinical examination, visual, auditory as well as
event-related potentials (P300).
Results:
The results of the study clarified that abnormal visual and auditory evoked
potentials were recorded in diabetic children. Meanwhile, abnormal (P300) latency was recorded in 47.6%
of diabetic children.
Conclusion:
This study clarified that peripheral as well as central nervous system
abnormalities are commonly observed in diabetic patients irrespective of
type of diabetes, severity and treatment. And these abnormalities may be
detected even before clinical manifestations appear. So that, early control
of diabetes may help to prevent the progress of these changes.