EVOLUTION OF BMC AND BMD IN
PRETERMS AND TERM NEONATES DURING THE SEVEN FIRST YEARS OF LIFE
M. Molina
Hoya; R. Santana Delgado; J. Garrido García; E. Narbona López; E. M. Sena
Ruiz.
Universitary
Hospital “San Cecilio”, Granada, Spain
Objective:
To show significative differences of BMC and BMD
between preterm and term neonates during these seven years.
Methods:
We study a group of 46 neonates followed during
seven years. 26 of then were preterm and 16 were term newborns. We measured
BMC and BMD using Hologic QDR-1000 TM (double X-ray densitometry), at
birth, 4 months, 1 and 7 years in each child. We also take note of weight,
high and craneal perimeter. These notes were compared using Man-Whitney
Test.
Results:
1 BMC
|
|
PRETERM
GROUP
|
TERM
GROUP
|
|
BIRTH
|
0.82±0.46gr.
|
1.88±0.57gr.
|
|
4
MONTHS
|
0.94±0.29gr.
|
1.75±0.46gr.
|
|
1
YEAR
|
3.36±1.35gr.
|
4.05±2.01gr.
|
|
7
YEARS
|
12.81±2.85gr.
|
12.49±2.47gr.
|
2 BMD
|
|
PRETERM
GROUP
|
TERM
GROUP
|
|
BIRTH
|
0.3854
±0.46
|
0.48
±0.04
|
|
4
MONTHS
|
0.3781
±0.04
|
0.4165
±0.02
|
|
1
YEAR
|
0.4316
±0.04
|
0.4511
±0.06
|
|
7
YEARS
|
0.598
±0.05
|
0.5661
±0.07
|
3
There are significative differences in BMC between preterm and term
children at birth (p<0,0001) and 4 months old (p<0,001) but not at 1
and 7 years old.
4
There are significative differences in BMD between preterm and term
children at birth (p<0,001) and 4 months old (p<0,025) but not at 1
and 7 years old.
5 Longitudinally there isn´t significative
difference of BMC from birth to 4 months in both groups. There is it from
birth to 1 year old.
6
Longitudinally there isn´t significative difference of BMD from birth to 4
months in preterm group. But in term group BMD is significativelly lower
(p<0,02) at 4 months compared to bith.
7
While in term group there isn´t significative difference in BMD from birth
to 1 year old, there is an important growth of BMD in preterm group during
this period (p<0,001).
Conclusions:
1 At
1 year old preterm group reachs term group BMC and BMD.
2
From birth to 4 months old the preterm group has a lower BMC and BMD than
the term group.
3 In
term group there is a fall of
BMD and BMC from birth to 4 months which is recuperated at 1 year
old.
4 At
7 years old there are no differences between both groups.