INITIAL
CLINICAL MANIFESTATIONS AND LONG-TERM FOLLOW UP OF JUVENILE-ONSET
SPONDYLOARTH-
ROPATHIES IN 40
CHILDREN
Zhao Shanrui, Zhou Qing
China-Japan Union
Hospital of Jilin University, Changchun, China
Objective: In order to study the
initial clinical manifestations, prognosis and influence on its correlation
factors in children with juvenile-onset spondyloarthropathies (JSPA).
Methods: Clinical data of 40
JSPA was analysed and follow-up study from 2 years to 15 years was made.
Results: 1. First manifestations
of onset disease: Joints of lower limbs are affected non-symmetricaly in
14/40 (35%,①). Sacroiliac joint or
joints are affected in 10/40 (25% ,②). Both ① and ② is affected in 11/40 (27.5%,③). Hand and feet are affected +① in 2/40 (5%,④). Spinal or feet are affected +② in 3/40 (7.5%,⑤). 2. Analysis of HLA-B27 HLA-B27 was
analysed in 36/40 with JSPA, 32 /36 were positive (88.89%). 3. Prognosis
15/40 were remitted (37.5%), 10 cases of them were present at regular
treating group (Ⅰ, 12 cases), 5 cases
were present at non-regular treating group (Ⅱ, 28 cases). (X2=15.36,
P<0.005);11/40 were deformited (27.5%), they were all present at Ⅱ (X2=6.5, P<0.05).
Deformitting time was about 2-11 years. Onset over and over again presents
at 12 cases. Recurrent type presents at 2 cases.
Conclusion: 1. Early manifestations
of JSPA were peripheral arthritis including lower limbs、sacroiliac joint (87.5%). 2. Positive
rate of HLA-B27 was about 88.89%. 3. Regular treatment can increase
remitting rate and decrease deformitting rate.