FROM
ATOPIC DERMATITIS TO ASTHMA, RISK FACTORS FOR THE ALLERGIC MARCH
I.Sokolovski, S.Antovska,
V.Butleska,
J.Minov
Public Health Facility,
Skopje, Macedonia
Objective: The prevalence of atopic
diseases increased during past three decades. The incidence of atopic
dermatitis (AD) is high during the first three mounts of life and is
important factor for manifestation of allergic airway diseases at 5 years
of age. It has been documented that 40% of children with AD will develop
allergic march to asthma. The recently study confirm that risk factors,
predictors for future asthma are family atopic hitory (atopic parent or
sibling) raised total IgE level, sensitisation to house dust mite,
sensitisation to grass polen. The aim of the study is to present between
our patients’ risk factors for development the allergic march from AD to
asthma.
Methods: Retrospective revew of
of 510 children born during the period of 1994 to 1998 year. Family atopic
history (parents or sibling), total IgE levels and specific IgE levels for
house dust mite, grass pollen were determined to all children with AD.
Results: From the group of 510
children diagnosis of AD was established at 71 (14%) children, 42 male and
29 female. Asthma developed 29 (40,4%). Positive family atopic history had
59 (83%) children. Total IgE levels
(>30uk/l) were raised at 61 (88,5%) children. Specific IgE levels
for house dust mite were raised at 25 (34,4 %) children, specific IgE
levels for grass pollen were raised at 17 (13,6%) children.
Conclusions: We have concluded that
allergic march from AD to asthma is reality. All mention risk factor
contribute in developing asthma from AD.