CLINICAL STUDY OF TREATMENT TO CHILDHOOD ASTHMA WITH AMINOPHYLLINE STEP-THERAPY

Yang X, Liu Z, Wang B, Fan Y

Tianjin Childrens Hospital, Tianjin, China

 

Objective: To study the effect of aminophyllin for treatment of childhood asthma.

Methods: 5mg/kg aminophlline was given in vein 3 time a day during acute status. In the catabasis, 80 patients were randomly divided into 4 group. 3mg/kg aminophylline was given orally 3 times a day to the treatment group (25 cases). The other 3 control groups were prescribed with Procaterol,Aminophylline plus Procaterol and herbal medicine respectively,and followed up for a year. Recurrent time, clnical effectness, lung function and blood aminophylline level were monitored.

Result: The clinical effectiveness and lung function of treatment group were improved significantly, and the recurrent is much less compaeing ti the control groups that took procaterol and herbal medicine. The blood aminophylline level was within the range of 5-6ug/ml. No side effects were detected.

Conclusion: Aminophylline can be taken as the first choice for treatment of childhood asthma with less side-effects. It is safe, convenience and lower price.

 
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