APPROACHING ON EVALUATING THE ETIOLOGY AND CLINICAL FEATURES OF NEONATAL HYPERBILIRUBINEMIA

Zhao XP1, Li QL2

12 Shanxi Provincial Children's Hospital, Taiyuan, China

 

Objective: To evaluate the etiology and clinical features of neonatal hyperbilirubinemia and the risk factors of kernicterus.

Method: 340 cases were divided into 5 groups according to their causes including perinatal risk factors, infection, breast feeding factor, hemolytic disease and unknown factor. The degree of jaundice, the changes of serum bilirubin concentration before and after treatment, periods and prognosis of 5 groups were compared respectively. The incidence of kernicterus of 5 groups were analysized according to their gestational age and day age.

Results: The incident rate of neonatal hyperbilirubinemia was 31.76% in group with perinatal factor, 25.29% in group with infection, 16.18% in group with breast feeding, 11.19% in group with hemolytic disease and 11.18% in group with unknown factors, respectively.

Conclusions: It is the key of preventing and treating neonatal hyperbilirubinemia to prevent dystocia, asphyxia and prematury by strengthening maternal and perinatal healthy care and finding out the causes of jaundice earlier.

 
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