FREQUENCY
OF CHROMOSOMAL ABNORMALITIES IN PERSONS OF POPULATION OF NOVI SAD
(YUGOSLAVIA) DURING NATO AIR STRIKES '99
Krstic
A, Madzar R, Gacina Lj, Cihi V, Popic-Paljic F, Jovanovic J, Obrenovic
M, Kavecan I, Popadic J, Petrovacki B, Redzek T, Nikolic M
Child
and Youth Health Care Institute, Department of Medical Genetics,
Cytogenetic Lab, Medical faculty of Novi Sad, Yugoslavia
During
NATO air strikes Novi Sad was bombed almost every day from March to June of
year 1999.
Objective: The aim was
to estimate chromosomal abnormalities by analyzing kariotypes of
peripheral, fetal blood and amniotic fluid fibroblasts of our patients.
Methods: We analyzed
kariotypes of peripheral and fetal blood cells and amniotic fluid
fibroblasts of 458 persons of different age groups. We compared results of
analyses from 1999 with those from the same period of time from a year
before (1998) and from the year after (2000).
Results: In the tests
of peripheral blood analyzed kariotypes, higher level of mutagenesis which
were significant has been estimated in 1999. compared with 1998. On the
other side, in the tests of amniotic fluid fibroblasts, higher level of
mutagenesis has not been found comparing 1998 with 1999. Comparison between
the results from 1999 with 2000 is showing that in the year 2000, after the
bombing, we have higher level of mutagenesis in the tests of amniotic fluid
fibroblasts, as well as in fetal blood analyses, but not in peripheral
blood.
Conclusion: Our results
are showing that during the bombing in 1999. mutagenesis was higher in
peripheral blood, but not in fibroblasts of amniotic fluids and fetal blood
cells. Later in 2000, we found higher mutagenesis in fibroblasts and
fetal blood cells, but not in peripheral blood of our patients. Detailed
analysis is in progress.