Sapan N, Alper Z, Canitez Y, Bilgel N, Ediz B

Uludag University, Dept. of Pediatric Allergy, Turkey


Wheezing in childhood is one of the most frequent symptom of childhood respiratory tract illnesses and is important not only of its acute morbidity, but also because it has been suggested that children with wheezing in early childhood may have a higher risk for asthma. Epidemiological studies from different countries showed that 25 % of children under 5 years had one kind of wheezing associated respiratory illness and one-third of these wheezy ınfants developed asthma later in life. We investigated the association between wheezing and prenatal, natal and postnatal, familial, and enviromental risk factors in 858 children aged 7 years in first classes of 7 primary schools randomly choosen in the metropolitan municipalty of Bursa via a questionnary which were filled in by parents. We found 107 children had early transient wheezing (12.4 %), 61 had persistent wheezing (7.1 %), 66 had late-onset wheezing (7.6 %) and 624 (72.7 %) never had wheezing. 33.3 % of children who had wheezing in first year had doctor-diagnosed asthma. Male sex, lower socioeconomic status, premature born, maternal smoking during pregnancy, bottle feeding before 2 months, dampness and mould at home, hospitalisation in infancy because of a respiratory tract illness, croup history during 6 months - 5 years, frequent upper respiratory tract infection in first 3 years, doctor-diagnosed asthma and allergic eczema of the child and any allergic disease of mother and siblings were more associated with wheezing of first 3 years. Breast feeding seemed to have protective effect against wheezing in first 3 years of life.