RISK FACTORS OF SEPSIS NEONATORUM IN DR. SOETOMO
HOSPITAL BETWEEN FEBRUARY 2000 AND FEBRUARY 2001
Fatimah Indarso, Retno Asih, Retna Hastuti, Risa
Etika, Agus Harianto, Sylviati M. Damanik, Soegeng Soegijanto
Child Health Department of Dr. Soetomo Hospital Surabaya, Sidoarjo,
Indonesia
Introduction: Infections of the
newborn and young infant are a significant cause of mortality and long term
morbidity. The incidence rates of neonatal sepsis in several refferal
hospitals in Indonesia is 1.5% - 3.72% with the mortality rate is 37.09% -
80%. These incidence rates vary from nursery to nursery and depend on
conditions predisposing to infection and the refferal system. The aim on
this study was to know the risk factors of sepsis neonatorum among the high
risk infants who delivered in neonatal intensive care unit Dr. Soetomo
Hospital between February 2000 and February 2001.
Methods: The study design was
cross sectional retrospective analysis. Technical sampling was purposive
sampling. Risk factors which were analyzed were premature, low birth
weight, premature rupture of membran, meconeal amniotic fluid, maternal
fever, apgar score, invasif procedure, sex and multiple gestation. The
exclusion criteria were if the infant discharged on request and if the
infant had congenital anomaly. Chi square test and logistic regression were
used to analyze the correlation between the incidence of sepsis neonatorum
with a set of variables. A p values less than 0.05 was considered
significant.
Results: From this study can
be determined :
- these were
significant statistically correlation between the incidence of sepsis
neonatorum with meconeal amniotic fluid, premature rupture of the membrane
and premature delivery (p = 0.0013; p = 0.0211; p = 0.0381 respectively)
Conclusion: Meconeal amniotic
fluid is the risk factor that have strong correlation with the incidence of
sepsis neonatorum in Dr. Soetomo Hospital.