THE CLININICAL AND EEG
CHARACTERISTICS OF INFANCY EPILEPSY OF TEMPORAL LOBE ORIGIN
Jinxing Liang,
Fangchen Cai
Department of Neurology,
Children¡¯s Hospital, Chongqing, China
Objective: The aim of study was to analyze the EEG, CT scan,
MRI and clinical manifestations in a cohort of 32 infancy epilepsy of
temporal lobe origin (IETLO).
Methods: Thirty-two IETLO including 19 males and 13 females
were subjected to the study. The onset of IETLO was between 2 and 34 months
with an average of 20 months, and 25 cases were followed up for one to six
years with the examinations of EEG, Videotapes, CT and MRI.
Results: IETLO was an age-related epileptic syndrome
characterized by a clinico-electrical features in infants aged less than
two years different from those in elder children. The seizure semiology was
atypical presentations including initial motionless stare, behavioral
arrest or reduction with possible impairment of consciousness in 27 cases,
autonomic features and oroalimentary or simple manual automatisms in 16
cases. Tonic, versive or Myoclonic seizures were observed in 13 cases, Most
of seizures lasted for more than 1 min. The interictal EEG indicated that
the epileptogenic discharges found in infants were less often than in elder
children with single or multiple foci. The ictal EEG discharges were less
localizde and not distinct in patterns. Video-EEG monitoring was useful to
observe the seizure patterns and consciousness. CT scans found structural
cerebral lesions in 5/6 cases and MRI gave more information of brain
lesions in 11/14 cases.
Conclusion: IETLO is an age-related epileptic syndrome
characterized by the clinico-electrical features as follows: motionless
stare, behavioral arrest or reduction with possible impairment of
consciousness, autonomic features and oroalimentary automatisms; Convulsive
seizures were prominent. The intericatal discharges were less found and
ictal discharges were less focal.Video-EEG monitoring was useful to observe
the seizure patterns and consciousness. Neuroimagings are important in
finding structural cerebral lesions.